Bundle of Joy:

Maternal & Infant Health Trends

Bundle of JoyTM:

Maternal & Infant Health Trends

Every new mother and child deserves the best beginning possible, at the most affordable price point. We’re working to make that possible. Premier’s Bundle of JoyTM Campaign is focused on ensuring mothers and babies are always at the center of care, and supported by the latest evidence, the best doctors and the most successful practices.


Premier provides the following resources for healthcare organizations to join us in our campaign to improve maternal and infant health.

+ Data-driven Insights

+ Maternal & Infant Outcomes Dashboard

+ Performance Improvement Services

+ New Payment Models & Policy

Learn more about the campaign

Every new mother and child deserves the best beginning possible, at the most affordable price point. We’re working to make that possible. Premier’s Bundle of JoyTM Campaign is focused on ensuring mothers and babies are always at the center of care, and supported by the latest evidence, the best doctors and the most successful practices.


Premier provides the following resources for healthcare organizations to join us in our campaign to improve maternal and infant health.

+ Data-driven Insights

+ Maternal & Infant Outcomes Dashboard

+ Performance Improvement Services

+ New Payment Models & Policy

Learn more about the campaign

Data-driven Insights:
The following maternal and infant health trends analysis leverages the Premier Healthcare Database and is used to help hospitals and the nation better understand and target solutions to this national problem. Premier’s analytic capabilities and data assets are used to study specific therapeutic interventions and assess clinical efficacy over time to implement new solutions for unmet medical needs. This is the first of several analyses on maternal and infant health trends.

Every new mother and child deserves the best beginning possible, at the most affordable price point. We’re working to make that possible. Premier’s Bundle of JoyTM Campaign is focused on ensuring mothers and babies are always at the center of care, and supported by the latest evidence, the best doctors and the most successful practices.


Premier provides the following resources for healthcare organizations to join us in our campaign to improve maternal and infant health.

+ Data-driven Insights

+ Maternal & Infant Outcomes Dashboard

+ Performance Improvement Services

+ New Payment Models & Policy

Learn more about the campaign

Maternal & Infant Outcomes Dashboard: 
The industry’s only integrated analytics dashboard enables a comprehensive analysis of an organization’s select perinatal and neonatal data sets, including peer-level and regional benchmarks and individualized reports assessing quality and outcomes. Premier continues to develop innovative analytics solutions to enable hospitals and health systems to benchmark and assess performance against its comprehensive maternal and infant database.

Every new mother and child deserves the best beginning possible, at the most affordable price point. We’re working to make that possible. Premier’s Bundle of JoyTM Campaign is focused on ensuring mothers and babies are always at the center of care, and supported by the latest evidence, the best doctors and the most successful practices.


Premier provides the following resources for healthcare organizations to join us in our campaign to improve maternal and infant health.

+ Data-driven Insights

+ Maternal & Infant Outcomes Dashboard

+ Performance Improvement Services

+ New Payment Models & Policy

Learn more about the campaign

Performance Improvement Services:
Premier provides one-to-one consulting support as well as collaborative initiatives to advance and scale national efforts to improve maternal and infant health. In July 2019, Premier announced it is working with 10 leading hospitals on a Perinatal Collaborative designed to reach zero preventable maternal and neonatal harm and deaths. Learnings from the collaborative will be shared nationally. In January 2020, the QUEST® quality improvement collaborative will launch a new perinatal specialty network to further test and adopt evidence-based strategies to improve care and the overall experience for women, infants and their families.

Every new mother and child deserves the best beginning possible, at the most affordable price point. We’re working to make that possible. Premier’s Bundle of JoyTM Campaign is focused on ensuring mothers and babies are always at the center of care, and supported by the latest evidence, the best doctors and the most successful practices.


Premier provides the following resources for healthcare organizations to join us in our campaign to improve maternal and infant health.

+ Data-driven Insights

+ Maternal & Infant Outcomes Dashboard

+ Performance Improvement Services

+ New Payment Models & Policy

Learn more about the campaign

New Payment Models and Policy:
Premier is working with private and public organizations to test and scale new payment models and reforms to improve maternal healthcare.

Every new mother and child deserves the best beginning possible, at the most affordable price point. We’re working to make that possible. Premier’s Bundle of JoyTM Campaign is focused on ensuring mothers and babies are always at the center of care, and supported by the latest evidence, the best doctors and the most successful practices.

 

Premier provides the following resources for healthcare organizations to join us in our campaign to improve maternal and infant health.

+ Data-driven Insights

+ Maternal & Infant Outcomes Dashboard

+ Performance Improvement Services

+ New Payment Models & Policy

Learn more about the campaign

Every new mother and child deserves the best beginning possible, at the most affordable price point. We’re working to make that possible. Premier’s Bundle of JoyTM Campaign is focused on ensuring mothers and babies are always at the center of care, and supported by the latest evidence, the best doctors and the most successful practices.

 

Premier provides the following resources for healthcare organizations to join us in our campaign to improve maternal and infant health.

+ Data-driven Insights

+ Maternal & Infant Outcomes Dashboard

+ Performance Improvement Services

+ New Payment Models & Policy

Learn more about the campaign

Data-driven Insights:
The following maternal and infant health trends analysis leverages the Premier Healthcare Database and is used to help hospitals and the nation better understand and target solutions to this national problem. Premier’s analytic capabilities and data assets are used to study specific therapeutic interventions and assess clinical efficacy over time to implement new solutions for unmet medical needs. This is the first of several analyses on maternal and infant health trends.

Every new mother and child deserves the best beginning possible, at the most affordable price point. We’re working to make that possible. Premier’s Bundle of JoyTM Campaign is focused on ensuring mothers and babies are always at the center of care, and supported by the latest evidence, the best doctors and the most successful practices.

 

Premier provides the following resources for healthcare organizations to join us in our campaign to improve maternal and infant health.

+ Data-driven Insights

+ Maternal & Infant Outcomes Dashboard

+ Performance Improvement Services

+ New Payment Models & Policy

Learn more about the campaign

Maternal & Infant Outcomes Dashboard: 
The industry’s only integrated analytics dashboard enables a comprehensive analysis of an organization’s select perinatal and neonatal data sets, including peer-level and regional benchmarks and individualized reports assessing quality and outcomes. Premier continues to develop innovative analytics solutions to enable hospitals and health systems to benchmark and assess performance against its comprehensive maternal and infant database.

Every new mother and child deserves the best beginning possible, at the most affordable price point. We’re working to make that possible. Premier’s Bundle of JoyTM Campaign is focused on ensuring mothers and babies are always at the center of care, and supported by the latest evidence, the best doctors and the most successful practices.

 

Premier provides the following resources for healthcare organizations to join us in our campaign to improve maternal and infant health.

+ Data-driven Insights

+ Maternal & Infant Outcomes Dashboard

+ Performance Improvement Services

+ New Payment Models & Policy

Learn more about the campaign

Performance Improvement Services:
Premier provides one-to-one consulting support as well as collaborative initiatives to advance and scale national efforts to improve maternal and infant health. In July 2019, Premier announced it is working with 10 leading hospitals on a Perinatal Collaborative designed to reach zero preventable maternal and neonatal harm and deaths. Learnings from the collaborative will be shared nationally. In January 2020, the QUEST® quality improvement collaborative will launch a new perinatal specialty network to further test and adopt evidence-based strategies to improve care and the overall experience for women, infants and their families.

Every new mother and child deserves the best beginning possible, at the most affordable price point. We’re working to make that possible. Premier’s Bundle of JoyTM Campaign is focused on ensuring mothers and babies are always at the center of care, and supported by the latest evidence, the best doctors and the most successful practices.

 

Premier provides the following resources for healthcare organizations to join us in our campaign to improve maternal and infant health.

+ Data-driven Insights

+ Maternal & Infant Outcomes Dashboard

+ Performance Improvement Services

+ New Payment Models & Policy

Learn more about the campaign

New Payment Models and Policy:
Premier is working with private and public organizations to test and scale new payment models and reforms to improve maternal healthcare.

Trend Analysis Key Findings

In July 2019, Premier conducted a national trend analysis to explore maternal and infant health outcomes in the hospital, at the time of delivery. The analysis leveraged the nationally representative Premier Healthcare Database and included standardized inpatient data from 8.9 million births that occurred in 903 hospitals across 45 states between 2008-2018. The data in the Premier analysis represent approximately 25 percent of all U.S. in-hospital births and were comparable in patient and hospital demographics to the data used by the Centers for Disease Control and Prevention (CDC) in its Vital Signs report on pregnancy-related deaths.

Comprised of nearly 20 years of de-identified inpatient data, Premier’s best-in-class database is more current and standardized than the CDC’s data. Therefore, Premier data can help provide policymakers and clinicians with additional insights into hospital performance on maternal health. This is Premier’s first analysis of maternal and infant mortality and morbidity, with additional analyses forthcoming.
 
Patient demographics and clinical outcomes were measured using the CDC’s methodology for severe maternal morbidity (SMM), which includes the birth admission definition as the denominator and the numerator, as well as additional standardized national methodologies. Note that as hospitals switched from ICD-9 to ICD-10 mid-way through 2015, changes in documentation and coding may have affected year 2015 trending in comparison with previous years.
Wrapping Highlighted Text Figure 1: Total Birth Volume by State

Total Birth Demoninator

Trend Analysis Key Findings

In July 2019, Premier conducted a national trend analysis to explore maternal and infant health outcomes in the hospital, at the time of delivery. The analysis leveraged the nationally representative Premier Healthcare Database and included standardized inpatient data from 8.9 million births that occurred in 903 hospitals across 45 states between 2008-2018. The data in the Premier analysis represent approximately 25 percent of all U.S. in-hospital births and were comparable in patient and hospital demographics to the data used by the Centers for Disease Control and Prevention (CDC) in its Vital Signs report on pregnancy-related deaths.

Comprised of nearly 20 years of de-identified inpatient data, Premier’s best-in-class database is more current and standardized than the CDC’s data. Therefore, Premier data can help provide policymakers and clinicians with additional insights into hospital performance on maternal health. This is Premier’s first analysis of maternal and infant mortality and morbidity, with additional analyses forthcoming.
 
Patient demographics and clinical outcomes were measured using the CDC’s methodology for severe maternal morbidity (SMM), which includes the birth admission definition as the denominator and the numerator, as well as additional standardized national methodologies. Note that as hospitals switched from ICD-9 to ICD-10 mid-way through 2015, changes in documentation and coding may have affected year 2015 trending in comparison with previous years.
Wrapping Highlighted Text Figure 1: Total Inpatient Birth Volume by State

Total Birth Demoninator

Wrapping Highlighted Text U.S. hospitals are demonstrating a dramatic decrease in delivery-related maternal deaths
U.S. hospitals are demonstrating a dramatic decrease in delivery-related maternal deaths
Overall, Premier found that U.S. hospitals showed a 24 percent decrease in delivery-related maternal deaths between 2008-2018 (Figure 2).

This trend suggests that progress is being made in the hospital, at the time of delivery. However, the analysis did not explore maternal deaths occurring outside of delivery in the hospital or preventability of these deaths. Additional occurrences of maternal mortality across the continuum of pregnancy will be explored in a later analysis.
Wrapping Highlighted Text Figure 2: In-Hospital, Delivery-Related Death Rate Trend
Chart JS
Premier worked closely with the CDC to ensure the methodology used in this analysis was aligned with and complemented their data. However, there are a several differences and details in Premier's findings compared to the CDC. For instance, Premier’s analysis shows a reduction in delivery-related maternal mortality rates within the hospital. This is because Premier’s data is more current, going through 2018 while the CDC’s most recent mortality trends end in 2015. Premier’s analysis was also conducted using standardized inpatient data, which allows for greater specificity when exploring trends happening within the hospital, at the time of delivery. These insights, however, are based only on inpatient stays. In comparison, the CDC uses mortality data from the National Vital Statistics System, death certificates from each state and the Pregnancy Mortality Surveillance System. The CDC defines a pregnancy-related death as the death of a woman during pregnancy or within one year of the end of pregnancy from a pregnancy complication, a chain of events initiated by pregnancy, or the aggravation of an unrelated condition by the physiologic effects of pregnancy.

While Premier’s analysis was limited to delivery-related hospitalizations and the CDC tracks maternal death outside of the hospital, the CDC has stated that “errors in reported pregnancy status on death certificates have been described, potentially leading to overestimation of the number of pregnancy-related deaths”. Premier’s in-hospital measure provides a more consistent assessment of facility performance.
Wrapping Highlighted Text Figure 3: Inpatient Maternal Death Rate for Cesarean Delivery
Chart JS
When comparing women who had a cesarean versus a vaginal delivery, Premier identified a slight increase in delivery-related maternal mortalities for vaginal deliveries (Figures 3 & 4).
Wrapping Highlighted Text Figure 4: Inpatient Maternal Death Rate for Vaginal Delivery
Chart JS
Notably, the disparity gap between black women and all other races for inpatient delivery-related deaths has substantially declined. Premier identified an 80 percent decrease in maternal mortality for black women between 2008-2018 (Figures 5, 6 & 7).
Wrapping Highlighted Text Figure 5: Inpatient Maternal Death Rate by Race - All Deliveries
Chart JS
Wrapping Highlighted Text Figure 6: Inpatient Maternal Death Rate During/After Vaginal Delivery by Race
Chart JS
Wrapping Highlighted Text Figure 7: Inpatient Maternal Death Rate for Cesarean Delivery by Race
Chart JS
Wrapping Highlighted Text Severe maternal morbidity has increased
While inpatient maternal mortality has decreased, the analysis showed an increase of 36 percent in severe maternal morbidity (SMM) between 2008-2018, and a 14 percent increase from 2015 through the end of 2018 (Figure 8). SMM includes unexpected outcomes of labor and delivery that result in significant short- or long-term health effects, including eclampsia, cardiac arrest and sepsis.
Wrapping Highlighted Text Figure 8: Overall SMM Rate
Chart JS
The increase in SMM rates could be due to several factors outlined below, including changes in coding, age, race, payer, type of delivery, substance use, region, hospital type and other factors.

 

As illustrated in Figure 9, the change from ICD-9 to ICD-10 may have affected the accuracy of SMM rates in year 2015. In other words, part of the increase may be attributable to coding and documentation changes. However, the Premier analysis showed a higher SMM rate than what was reported by the CDC for the same time period. This suggests that there may have been an increase in SMM rates regardless of the transition to ICD-10.
Wrapping Highlighted Text Figure 9: SMM Rate Change: ICD-9 versus ICD-10
Viewing by year, SMM rates increased by 14 percent between 2008-2012, then remained flat or even slightly decreased in 2013 and 2014. As illustrated in Figure 10, these findings are closely aligned with the CDC’s findings over this same time period. However, the CDC's SMM data is only available through 2014. In contrast, Premier’s analysis shows a slightly higher rate post ICD-10 implementation (2015) than what was observed by the CDC. Of note is the large increase in SMM rate in 2016 (19 percent) and the decrease in SMM rate (3 percent) in 2018.
Wrapping Highlighted Text Figure 10: Overall SMM Rate Comparison to CDC Data
Overall, blood transfusions, disseminated intravascular coagulation, hysterectomy, heart failure and sepsis were the top factors associated in patients who experienced a SMM as defined by the CDC (Figure 11). Blood transfusion incidence in this analysis is 34 percent higher compared to all other conditions and complications that constitute SMM. It is well recognized that blood transfusions are associated with women who have a higher risk of SMM and mortality. Transfusions are often used as a lifesaving measure in obstetrical hemorrhaging patients and other critical events. The clinical conditions triggering these transfusions and direct relationship to clinical outcomes have not been well described and provide an opportunity for further study.
Wrapping Highlighted Text Figure 11: Top 10 Diagnoses and Procedures Associated with SMM
Animated Horizontal Bar Graph
SMM Rates for Individual Diagnoses/SMM Procedures
  • Blood Transfusion
  • Disseminated Intravascular Coagulation
  • Hysterectomy
  • HF/Arrest During Procedure
  • Sepsis
  • ARDS
  • Eclampsia
  • Acute Renal Failuer
  • Shock
  • Acute/HF Pulmonary Edema
  • 107.1
  • 25.3
  • 15.5
  • 15.2
  • 10.5
  • 9.9
  • 8.9
  • 7.2
  • 5.9
  • 4.8
020406080100120
SMM Rate per 10,000 Deliveries
Premier’s analysis also identified the proportion of maternal complications attributable to various direct causes of SMM, which include cardiovascular conditions (21.3 percent), obstetric hemorrhage (24.6 percent), hypertensive disorders (11.4 percent), sepsis (6.4 percent), stroke (2.1 percent) and embolism (4.5 percent). Further study to determine indirect causes, such as preexisting conditions, maternal mental health and substance use, will be conducted in later Premier analysis.
Wrapping Highlighted Text The race disparity gap remains open for SMM
Black women had a 79 percent higher SMM rate than white women (Figure 12). Specifically, black women had higher SMM rates for heart failure, acute respiratory distress syndrome, eclampsia, acute renal failure and sepsis. Black women also have a 94 percent higher rate of blood transfusions than white women.
Wrapping Highlighted Text Figure 12: Overall SMM Rate by Maternal Race
Animated Horizontal Bar Graph
SMM Rates for Individual Diagnoses/SMM Procedures
  • Overall SMM Rate
  • Black
  • White
  • 181.2
  • 284.0
  • 155.3
050100150200250300
Patiens with Severe Maternal Morbidity per 10,000 Total Devlieries
Wrapping Highlighted Text Figure 13: Overall SMM Rate by Maternal Race
Chart JS
Disparities among black women compared to all other populations is evident. More research is needed to understand the specific attributes affecting the variation in hospital performance and SMM rates associated with these disparities.
Wrapping Highlighted Text The maternal population is aging
Another consistent trend in the analysis is the aging of the U.S. maternal population. The percent of women giving birth who are older than 35 years of age increased by 24 percent and by 12 percent for mothers 25-35. Women giving birth under the age of 25 decreased by 29 percent (Figure 14).
Wrapping Highlighted Text Figure 14: Overall Inpatient Maternal Age Distribution
Mothers older than 35 tend to have a higher rate of cesarean sections as illustrated in Figure 15. Cesarean deliveries, which can increase the risk of complications, are 41 percent more common for women older than 35 as compared to women younger than 35.
Wrapping Highlighted Text Figure 15: Cesarean Deliveries by Age Group
Chart JS
Overall, the SMM rate for patients aged 35 and older is 32 percent higher than those younger than 35. Although mothers older than 45 years demonstrate the highest risk for SMM, women between the ages of 15 – 24 experienced the greatest increases in SMM rates with a 51 percent increase, followed by those 25 – 34 at 35 percent, and a 28 percent increase for mothers ages 35 – 44. Those under the age of 15 demonstrated a 13 percent decrease in SMM (Figure 16).
Wrapping Highlighted Text Figure 16: Overall SMM Rate by Maternal Age Group
Chart JS
Overall, the rate of cesarean deliveries has declined slightly (Figure 17). 
Wrapping Highlighted Text Figure 17: Overall Cesarean Rate Trend
Chart JS
Premier’s analysis confirmed that SMM rates for cesareans are higher than for vaginal deliveries. However, SMM rates for vaginal deliveries have increased by 67 percent since 2015 (Figure 18). Note that much of this increase could be attributed to coding changes. The actual SMM rate decreased in 2017 and 2018 over 2016, after three full years of ICD-10.
Wrapping Highlighted Text Figure 18: Overall SMM Rate by Type of Delivery
Chart JS
Due to the differences between Premier’s and the CDC’s findings for SMM trends, additional analyses and research are needed to identify how coding changes may contribute to the SMM trend. For example, the changes in coding may demonstrate an enhanced capability to identify complications and SMM at a greater level of accuracy, thus enabling a better understanding of preventable harm and complications associated with pregnancy.
Wrapping Highlighted Text Patients with commercial insurance have the lowest SMM rates
Women with commercial insurance had the lowest SMM rates. Mothers with charity/indigent coverage had the highest SMM rates – a 71 percent higher SMM rate than commercial insurance carriers. Mothers with Medicaid had the second highest SMM rate – 32 percent higher than commercial carriers (Figure 19). In Premier’s analysis, 42 percent of women were covered by Medicaid and 50 percent by commercial insurance. The remaining 8 percent were covered through charity, indigent or other payment sources.
Wrapping Highlighted Text Figure 19: Overall SMM Rate by Type of Payer
Chart JS
Comparing rural to urban hospitals, SMM rates remained relatively the same, with a 50 percent increase for rural and 39 percent increase for urban hospitals from 2008 – 2018 (Figure 20).
Wrapping Highlighted Text Figure 20: SMM Rates for Rural VS Urban Hospitals
Chart JS
Comparing SMM rate by census region, hospitals in the Mid-Atlantic region had the highest SMM rates over the past four years. Hospitals in the Mountain region had the lowest rates over the past four years (Figure 21).
Wrapping Highlighted Text Figure 21: SMM Rates by Census Region
Chart JS
There are several other factors that could have influenced the increase in SMM rates. Premier plans to perform follow-up analyses to identify the key drivers, as well as how age, race, payer, type of delivery, region, hospital type, substance use and other factors may be influencing SMM rates.
Wrapping Highlighted Text Maternal Substance Use and Neonatal Abstinence Syndrome
Alarmingly, the rate of infants born with neonatal abstinence syndrome (NAS) has increased by 140 percent since 2008 (Figure 22).
Wrapping Highlighted Text Figure 22: Rate of Babies born with Neonatal Abstinence Syndrome
Chart JS
The increasing rate of NAS aligned closely with an increased trend for birth mothers with documented substance use, which has increased by 153 percent since 2008 overall. Additionally, these mothers are 221 percent more likely to experience a SMM (Figure 23).
Wrapping Highlighted Text Figure 23: Birth Mothers with Documented Substance Use
Chart JS
When comparing rural to urban hospitals, rural hospitals had a 34 percent higher rate of maternal patients with substance misuse (Figure 24).
Wrapping Highlighted Text Figure 24: Rate of Substance Use by Hospital Location
Chart JS
Wrapping Highlighted Text U.S. hospitals are demonstrating a dramatic decrease in delivery-related maternal deaths
U.S. hospitals are demonstrating a dramatic decrease in delivery-related maternal deaths
Overall, Premier found that U.S. hospitals showed a 24 percent decrease in delivery-related maternal deaths between 2008-2018 (Figure 2).
 
This trend suggests that progress is being made in the hospital, at the time of delivery. However, the analysis did not explore maternal deaths occurring outside of delivery in the hospital or preventability of these deaths. Additional occurrences of maternal mortality across the continuum of pregnancy will be explored in a later analysis.
Wrapping Highlighted Text Figure 2: In-Hospital, Delivery-Related Death Rate Trend
Premier worked closely with the CDC to ensure the methodology used in this analysis was aligned with and complemented their data. However, there are a several differences and details in Premier's findings compared to the CDC. For instance, Premier’s analysis shows a reduction in delivery-related maternal mortality rates within the hospital. This is because Premier’s data is more current, going through 2018 while the CDC’s most recent mortality trends end in 2015. Premier’s analysis was also conducted using standardized inpatient data, which allows for greater specificity when exploring trends happening within the hospital, at the time of delivery. These insights, however, are based only on inpatient stays. In comparison, the CDC uses mortality data from the National Vital Statistics System, death certificates from each state and the Pregnancy Mortality Surveillance System. The CDC defines a pregnancy-related death as the death of a woman during pregnancy or within one year of the end of pregnancy from a pregnancy complication, a chain of events initiated by pregnancy, or the aggravation of an unrelated condition by the physiologic effects of pregnancy.

While Premier’s analysis was limited to delivery-related hospitalizations and the CDC tracks maternal death outside of the hospital, the CDC has stated that “errors in reported pregnancy status on death certificates have been described, potentially leading to overestimation of the number of pregnancy-related deaths”. Premier’s in-hospital measure provides a more consistent assessment of facility performance.
Wrapping Highlighted Text Figure 3: Inpatient Maternal Death Rate During/After Cesarean Delivery
When comparing women who had a cesarean versus a vaginal delivery, Premier identified a slight increase in delivery-related maternal mortalities for vaginal deliveries (Figures 3 & 4).
Wrapping Highlighted Text Figure 4: Inpatient Maternal Death Rate After/During Vaginal Delivery
Notably, the disparity gap between black women and all other races for inpatient delivery-related deaths has substantially declined. Premier identified an 80 percent decrease in maternal mortality for black women between 2008-2018 (Figures 5, 6 & 7).
Wrapping Highlighted Text Figure 5: Inpatient Maternal Death Rate by Race - All Deliveries
Wrapping Highlighted Text Figure 6: Inpatient Maternal Death Rate During/After Vaginal Delivery by Race
Wrapping Highlighted Text Figure 7: Inpatient Maternal Death Rate After/During Cesarean Delivery by Race
Wrapping Highlighted Text Severe maternal morbidity has increased
While inpatient maternal mortality has decreased, the analysis showed an increase of 36 percent in severe maternal morbidity (SMM) between 2008-2018, and a 14 percent increase from 2015 through the end of 2018 (Figure 7). SMM includes unexpected outcomes of labor and delivery that result in significant short- or long-term health effects, including eclampsia, cardiac arrest and sepsis.
Wrapping Highlighted Text Figure 8: Overall SMM Rate
The increase in SMM rates could be due to several factors outlined below, including changes in coding, age, race, payer, type of delivery, substance use, region, hospital type and other factors. 

 

As illustrated in Figure 9, the change from ICD-9 to ICD-10 may have affected the accuracy of SMM rates in year 2015. In other words, part of the increase may be attributable to coding and documentation changes. However, the Premier analysis showed a higher SMM rate than what was reported by the CDC for the same time period. This suggests that there may have been an increase in SMM rates regardless of the transition to ICD-10.
Wrapping Highlighted Text Figure 9: SMM Rate Change: ICD-9 versus ICD-10
Viewing by year, SMM rates increased by 14 percent between 2008-2012, then remained flat or even slightly decreased in 2013 and 2014. As illustrated in Figure 10, these findings are closely aligned with the CDC’s findings over this same time period. However, the CDC's SMM data is only available through 2014. In contrast, Premier’s analysis shows a slightly higher rate post ICD-10 implementation (2015) than what was observed by the CDC. Of note is the large increase in SMM rate in 2016 (19 percent) and the decrease in SMM rate (3 percent) in 2018.
Wrapping Highlighted Text Figure 10: Overall SMM Rate Comparison to CDC Data
Overall, blood transfusions, disseminated intravascular coagulation, hysterectomy, heart failure and sepsis were the top factors associated in patients who experienced a SMM as defined by the CDC (Figure 11). Blood transfusion incidence in this analysis is 34 percent higher compared to all other conditions and complications that constitute SMM. It is well recognized that blood transfusions are associated with women who have a higher risk of SMM and mortality. Transfusions are often used as a lifesaving measure in obstetrical hemorrhaging patients and other critical events. The clinical conditions triggering these transfusions and direct relationship to clinical outcomes have not been well described and provide an opportunity for further study.
Wrapping Highlighted Text Figure 11: Top 10 Diagnoses and Procedures Associated with SMM
Premier’s analysis also identified the proportion of maternal complications attributable to various direct causes of SMM, which include cardiovascular conditions (21.3 percent), obstetric hemorrhage (24.6 percent), hypertensive disorders (11.4 percent), sepsis (6.4 percent), stroke (2.1 percent) and embolism (4.5 percent). Further study to determine indirect causes, such as preexisting conditions, maternal mental health and substance use, will be conducted in later Premier analysis.
Wrapping Highlighted Text The race disparity gap remains open for SMM
Black women had a 79 percent higher SMM rate than white women (Figure 12). Specifically, black women had higher SMM rates for heart failure, acute respiratory distress syndrome, eclampsia, acute renal failure and sepsis. Black women also have a 94 percent higher rate of blood transfusions than white women. 
Wrapping Highlighted Text Figure 12: Overall SMM Rate by Maternal Race
Wrapping Highlighted Text Figure 13: Overall SMM Rate by Maternal Race
Disparities among black women compared to all other populations is evident. More research is needed to understand the specific attributes affecting the variation in hospital performance and SMM rates associated with these disparities.
Wrapping Highlighted Text The maternal population is aging
Another consistent trend in the analysis is the aging of the U.S. maternal population. The percent of women giving birth who are older than 35 years of age increased by 24 percent and by 12 percent for mothers 25-35. Women giving birth under the age of 25 decreased by 29 percent (Figure 14).
Wrapping Highlighted Text Figure 14: Overall Maternal Age Distribution
Mothers older than 35 tend to have a higher rate of cesarean sections as illustrated in Figure 15. Cesarean deliveries, which can increase the risk of complications, are 41 percent more common for women older than 35 as compared to women younger than 35.
Wrapping Highlighted Text Figure 15: Cesarean Deliveries by Age Group
Overall, the SMM rate for patients aged 35 and older is 32 percent higher than those younger than 35. Although mothers older than 45 years demonstrate the highest risk for SMM, women between the ages of 15 – 24 experienced the greatest increases in SMM rates with a 51 percent increase, followed by those 25 – 34 at 35 percent, and a 28 percent increase for mothers ages 35 – 44. Those under the age of 15 demonstrated a 13 percent decrease in SMM (Figure 16).
Wrapping Highlighted Text Figure 16: Overall SMM Rate by Maternal Age Group
Overall, the rate of cesarean deliveries has declined slightly (Figure 17). 
Wrapping Highlighted Text Figure 17: Overall SMM Rate by Type of Delivery
Premier’s analysis confirmed that SMM rates for cesareans are higher than for vaginal deliveries. However, SMM rates for vaginal deliveries have increased by 67 percent since 2015 (Figure 18). Note that much of this increase could be attributed to coding changes. The actual SMM rate decreased in 2017 and 2018 over 2016, after three full years of ICD-10.
Wrapping Highlighted Text Figure 18: Overall SMM Rate by Type of Delivery
Due to the differences between Premier’s and the CDC’s findings for SMM trends, additional analyses and research are needed to identify how coding changes may contribute to the SMM trend. For example, the changes in coding may demonstrate an enhanced capability to identify complications and SMM at a greater level of accuracy, thus enabling a better understanding of preventable harm and complications associated with pregnancy.
Wrapping Highlighted Text Commercial insurance carriers have the lowest SMM rates
Women with commercial insurance had the lowest SMM rates. Mothers with charity/indigent coverage had the highest SMM rates – a 71 percent higher SMM rate than commercial insurance carriers. Mothers with Medicaid had the second highest SMM rate – 32 percent higher than commercial carriers (Figure 19). In Premier’s analysis, 42 percent of women were covered by Medicaid and 50 percent by commercial insurance. The remaining 8 percent were covered through charity, indigent or other payment sources.
Wrapping Highlighted Text Figure 19: Overall SMM Rate by Type of Payer
Comparing rural to urban hospitals, SMM rates remained relatively the same, with a 50 percent increase for rural and 39 percent increase for urban hospitals from 2008 – 2018 (Figure 20).
Wrapping Highlighted Text Figure 20: SMM Rates for Rural VS Urban Hospitals
Comparing SMM rate by census region, hospitals in the Mid-Atlantic region had the highest SMM rates over the past four years. Hospitals in the Mountain region had the lowest rates over the past four years (Figure 21).
Wrapping Highlighted Text Figure 21: SMM Rates by Census Region
There are several other factors that could have influenced the increase in SMM rates. Premier plans to perform follow-up analyses to identify the key drivers, as well as how age, race, payer, type of delivery, region, hospital type, substance use and other factors may be influencing SMM rates.
Wrapping Highlighted Text Materna;l Substance Use and Neonatal Abstinence Syndrome
Alarmingly, the rate of infants born with neonatal abstinence syndrome (NAS) has increased by 140 percent since 2008 (Figure 22).
Wrapping Highlighted Text Figure 22: Rate of Babies born with Neonatal Abstinence Syndrome
The increasing rate of NAS aligned closely with an increased trend for birth mothers with documented substance use, which has increased by 153 percent since 2008 overall. Additionally, these mothers are 221 percent more likely to experience a SMM (Figure 23).
Wrapping Highlighted Text Figure 23: Birth Mothers with Documented Substance Use
When comparing rural to urban hospitals, rural hospitals had a 34 percent higher rate of maternal patients with substance misuse (Figure 24).
Wrapping Highlighted Text Figure 24: Rate of Substance Use by Hospital Locatione

Conclusions

In the United States, we have a limited understanding of why women are dying, or nearly dying, during pregnancy and childbirth. Unfortunately, state departments of health have limited sources of consistent, detailed data required to conduct accurate population-level analyses of maternal and infant health outcomes.
 
Premier's analysis showed that hospitals are making progress in reducing maternal deaths. It also showed that the disparity gap has narrowed for maternal mortality among black women at the time of delivery, in the hospital setting. However, SMM rates have increased, likely a result of multifactorial causes that will require additional detailed analyses. This will include deeper study of the migration to ICD-10 and how that change affected the calculation of quality measures. The disparity gap for SMM remains wide when comparing black women to all other races. Additionally, the maternal population is aging and demonstrating a higher rate of cesarean sections and complications. Caesarean delivery rates are decreasing, although they continue to have higher associated SMM than vaginal deliveries.

 

Substance misuse remains a serious public health concern, and has been linked to harmful maternal and infant outcomes.  Premier’s analysis demonstrates substantial increases in substance use among women who are pregnant, an alarming increase in the number of babies born with NAS. The analysis confirmed SMM is significantly higher among women with substance use disorders.

 

There are several factors that occur outside of the hospital during pre- and post-natal care that could be influencing overall maternal mortality and morbidity trends identified in Premier's analysis. The U.S. healthcare system continues to be fragmented in the way it cares for pregnant women, new mothers and infants. A more integrated approach to the care expectant and new mothers receives before, during and after delivery is needed in order to improve overall maternal and infant health in the United States.

 

Comprised of nearly 20 years of de-identified inpatient data, Premier’s database is best-in-class and provides focused insights and are more specific than what has been reported by the CDC. Premier will continue to leverage the scale and depth of its database, which offers healthcare providers, patients, policymakers and industry organizations authoritative guidance on improving the quality, safety and efficiency of care delivered across the continuum.

Conclusions

In the United States, we have a limited understanding of why women are dying, or nearly dying, during pregnancy and childbirth. Unfortunately, state departments of health have limited sources of consistent, detailed data required to conduct accurate population-level analyses of maternal and infant health outcomes.
 
Premier's analysis showed that hospitals are making progress in reducing maternal deaths. It also showed that the disparity gap has narrowed for maternal mortality among black women at the time of delivery, in the hospital setting. However, SMM rates have increased, likely a result of multifactorial causes that will require additional detailed analyses. This will include deeper study of the migration to ICD-10 and how that change affected the calculation of quality measures. The disparity gap for SMM remains wide when comparing black women to all other races. Additionally, the maternal population is aging and demonstrating a higher rate of cesarean sections and complications. Caesarean delivery rates are decreasing, although they continue to have higher associated SMM than vaginal deliveries.

 

Substance misuse remains a serious public health concern, and has been linked to harmful maternal and infant outcomes.  Premier’s analysis demonstrates substantial increases in substance use among women who are pregnant, an alarming increase in the number of babies born with NAS. The analysis confirmed SMM is significantly higher among women with substance use disorders.

 

There are several factors that occur outside of the hospital during pre- and post-natal care that could be influencing overall maternal mortality and morbidity trends identified in Premier's analysis. The U.S. healthcare system continues to be fragmented in the way it cares for pregnant women, new mothers and infants. A more integrated approach to the care expectant and new mothers receives before, during and after delivery is needed in order to improve overall maternal and infant health in the United States.

 

Comprised of nearly 20 years of de-identified inpatient data, Premier’s database is best-in-class and provides focused insights and are more specific than what has been reported by the CDC. Premier will continue to leverage the scale and depth of its database, which offers healthcare providers, patients, policymakers and industry organizations authoritative guidance on improving the quality, safety and efficiency of care delivered across the continuum.

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- Thomas F. Zenty III, CEO of University Hospitals

Leaders who act now can be winners.

The key is to have a comprehensive margin improvement strategy that is focused on reducing variation and costs, while also uncovering new revenue lines to offset diminishing reimbursement. Premier’s five keys to maximizing value are essential to achieve systemic and strategic transformations; alleviate margin pressures; improve efficiency and productivity; and maintain high-quality care.

“Premier has been a strategic partner in our effort to deliver high-value care while achieving our long-term financial goals. We have built a healthcare system that puts the patient front-and-center with regard to every decision we make and every strategic initiative we deploy.”

- Thomas F. Zenty III, CEO of University Hospitals

Leaders who act now can be winners.

The key is to have a comprehensive margin improvement strategy that is focused on reducing variation and costs, while also uncovering new revenue lines to offset diminishing reimbursement. Premier’s five keys to maximizing value are essential to achieve systemic and strategic transformations; alleviate margin pressures; improve efficiency and productivity; and maintain high-quality care.